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tepA [2017-8-11 16:0:3]
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tepA [2017-8-11 16:0:3]

orphan ClpP-like germination protease, contributes to SASP degradation
Locus
BSU16790
Isoelectric point
5.57
Molecular weight
24.10 kDa
Protein length
223 aa Sequence Blast
Gene length
669 bp Sequence Blast
Function
degradation of SASPs
Product
germination protease
Essential
no
Synonyms
ymfB, ylxI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Proteolysis → Proteolysis during sporulation/ germination
  • Lifestyles → Sporulation → Germination → Additional germination proteins

    • Gene

    Coordinates
    1,751,201 → 1,751,938

    The protein

    Catalyzed reaction/ biological activity

  • degradation of SASPs in germinating spores PubMed

    • Protein family

  • TepA subfamily (according to Swiss-Prot)

    • Effectors of protein activity

  • activity requires YlzJ PubMed

    • Localization

  • inner spore membrane PubMed

    • Expression and Regulation

    Operons

    Genes
    tepA-ylzJ
    Description
    PubMed

    Sigma factors

  • SigG: sigma factor, PubMed, in SigG regulon

    • Regulatory mechanism

  • SpoVT: repression, PubMed, in SpoVT regulon

    • Regulation

  • expressed late during sporulation in the forespore (SigG, SpoVT) PubMed
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    Biological materials

    Mutant

  • MGNA-B377 (ymfB::erm), available at the NBRP B. subtilis, Japan
  • GP1120 (spc), available in the Stülke lab

    • References

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